Zone Director, West

Mirum Pharmaceuticals

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US Remote Until 8/21/2026 5+ years exp H-1B sponsor history First posted June 6, 2026 Last posted June 6, 2026
Job description

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

POSITION SUMMARY 

The Zone Director is a second-line field leader responsible for driving commercial performance, building 4 high-performing Region Business Director (RBD) teams, and ensuring execution excellence across the liver portfolio. This role translates national strategy into regional impact, with a strong emphasis on rare disease expertise, patient-centricity, and cross-functional leadership.

Assigned Area: WA, OR, CA, NV, AZ, UT, ID MT, WY, CO, NM, TX, KS, SD, ND, OK. LA, AR, MO, IA, MN, WI, IL, KY, MS, AL

JOB FUNCTIONS/RESPONSIBILITIES

Enterprise Leadership

  • Own and deliver Zone business performance across the liver portfolio with a strategic, big-picture mindset
  • Drive change and innovation
  • Develop and execute zone-specific business plans aligned to national strategy
  • Analyze market trends, competitive dynamics, and performance data to inform actions

Team Leadership & Development

  • Lead, coach, and develop first-line leaders to maximize team effectiveness
  • Build a strong leadership pipeline and succession plans
  • Foster a culture of accountability, engagement, and continuous improvement

Execution Excellence

  • Ensure consistent and high-quality execution of brand strategy in the field
  • Monitor KPIs and drive disciplined performance management
  • Identify and scale best practices across regions

Cross-Functional Collaboration 

  • Partner with Marketing, Market Access, Medical Affairs, Patient Services and Operations
  • Ensure alignment on strategy and coordinated execution
  • Provide field insights to inform brand planning and lifecycle strategy

Market & Customer Engagement

  • Maintain strategic relationships with key opinion leaders (KOLs) and top accounts
  • Understand regional nuances in referral patterns and treatment pathways
  • Support teams in navigating complex access and reimbursement environments 

Compliance & Ethical Leadership

  • Ensure all activities comply with regulatory, legal, and company policies
  • Model integrity and patient-first decision making
  • Reinforce a culture of compliance across the organization 

QUALIFICATIONS

Education/Experience:

  • Bachelor’s degree required; advanced degree preferred (MBA, etc.)
  • 7+ years pharmaceutical/biotech experience, plus minimum of 5 years of leadership experience
  • Successful experience leading leaders (second-line leadership) highly desired
    • Significant rare disease and/or specialty experience
    • Experience in rare liver disease a plus
    • Proven success in product launches, ideally with first-in-class therapies and in competitive markets
    • Demonstrated ability to build, lead, train and develop high-performing teams
    • Proven success in sales leadership roles with the ability to inspire, influence and align teams
  • Experience navigating complex rare disease patient journeys, including diagnosis, referral pathways, and difficult access to therapies
  • Strong leadership presence with the ability to inspire, influence, and align teams
  • Strong understanding of market access, payer dynamics, and patient services
  • Demonstrated ability to lead in a matrixed organization
  • High integrity, ethical standards, and commitment to compliance
  • Thrives in a fast-paced, dynamic, and collaborative environment
  • Able to travel frequently, up to 70% overnight travel and has a valid drivers’ license

#LI-REMOTE

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.

Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.

 

About this role

Summary

Lead regional teams, drive business performance, ensure strategic execution in liver portfolio.

Job title

Zone Director, West

Experience level

7+ years pharmaceutical/biotech, 5+ years leadership

Minimum experience

5+ years exp

Industry

biopharmaceutical

Location requirements

US remote work allowed, frequent travel up to 70%

Salary

Not specified

Visa sponsorship

H-1B sponsor history

Management role

Yes

Skills & keywords

Required skills

leadershipbiopharmarare diseasemarket accesscompliance

Preferred skills

team developmentproduct launchespayerscustomer engagement

Specializations

rare diseasemarket accesspatient journeyproduct launches
Locations

Structured locations inferred from the posting.

United States

Remote Country