Staff Software Engineer - Commercial - #4903

GRAIL

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Sunnyvale, CA hybrid Until 9/20/2026 8+ years exp H-1B sponsor history First posted July 22, 2026 Last posted July 22, 2026
Job description
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
 
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
 
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
 
For more information, please visit grail.com

Grail is looking for a Staff level full-stack engineer who enjoys working on a broad array of software systems and projects. The team is responsible for patient-facing software used for The Galleri® Test as well as gathering clinical data. We strive to build a robust and scalable infrastructure as well as easy-to-use UI interfaces. Our technical stack consists of Go, AWS, Kubernetes, Microservices, and React.

This role is based in Sunnyvale, California. We are moving to our new headquarters in September so you may visit us at our current Menlo Park, CA offices during the interivew process. GRAIL offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale, CA campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities. We may also consider candidates in Durham NC but the bay area is preferred.

Responsibilities

  • Use your experience developing backend applications and distributed systems to build native cloud-based software that is leveraged by GRAIL’s key commercial offerings for the Galleri® Test , my.grail.com and provider.grail.com

  • Develop and lead multiple large cross-functional / cross-organizational programs with high complexity, resource requirements and associated risks.

  • Drive improvements for the software engineering organization based on understanding of business needs and industry trends

  • Provide technical leadership in the form of standards, tools, and knowledge requirements for the software engineering organization

  • Guide and mentors team members to provide an example of innovation and excellence

    •  

Required Qualifications

    • Bachelor's or Master's degree in Computer Science, Electrical Engineering, Bioinformatics, or similar technical field or equivalent experience.

    • 8-12+ years of meaningful work experience designing, developing, testing, and maintaining full-stack applications and microservice ecosystems.

    • Excellent knowledge of:

      • Programming Languages: Go (preferred), Java, Python, JavaScript, C++

      Frontend: React, Angular

      Backend: Spring, Spring Boot, REST APIs, gRPC (preferred)

      Cloud & DevOps: AWS (preferred), GCP, Azure, Kubernetes, Docker, Terraform (preferred), Microservices

      Data: PostgreSQL, MySQL, Redis

      Development Practices: CI/CD, Automated Testing, Agile Development

      • Experience developing distributed systems on one of the cloud platforms like AWS, GCP, or Azure.

      • Experience with writing and executing test protocols

      • Passion for designing and building practical high-quality software solutions.

      • Strong professional written and verbal communication skills.

      • Familiarity with gRPC, terraform, AWS is a plus

      • Willingness to add value to the team!

        • These job duties summarize the primary responsibilities of the position and are not intended to be a comprehensive listing of all duties. Responsibilities may change based on business needs.

The expected, full-time, annual base pay scale for this position is $169k-224k in the bay area. 

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
 
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.
 
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!
About this role

Summary

Develop and lead full-stack, microservices, and cloud-based software for cancer detection.

Job title

Staff Software Engineer - Commercial - #4903

Experience level

8-12+ years

Minimum experience

8+ years exp

Industry

healthcare

Location requirements

based in Sunnyvale, CA; flexible work with 60% on-site

Salary

$169k–$224k

Visa sponsorship

H-1B sponsor history

Management role

No

Skills & keywords

Required skills

goreactawskubernetesmicroservicesrest APIpythonjavac++pgmysql

Preferred skills

gRPCterraformgcpazureautomated testing

Specializations

full-stackmicroservicescloud computingdistributed systemsreact
Locations

Structured locations inferred from the posting.

Sunnyvale, CA, USA

Hybrid City
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