Sr. Staff, Instrument Software Engineer

About AtlasBase

AtlasBase is a fast-growing pioneer in Molecular Computing, bridging the gap between traditional IT and biotechnology. We are redefining global IT infrastructure by driving breakthroughs in both Molecular Compute and Molecular Data Storage. By commercializing synthetic DNA-based technologies at IT scale, AtlasBase delivers ultra-high-density, low-maintenance, and carbon-conscious solutions built for the explosive growth and value of the world's data. Leveraging nature’s most durable medium, we provide a virtually permanent foundation that transforms how the world processes and secures its most critical information.

Originally spun out of Twist Bioscience, our team is an elite fusion of scientists, engineers, and operators dedicated to solving some of the most complex infrastructure challenges on Earth. While our work is grounded in deep science, our success depends on world-class talent across every discipline. We are seeking a Sr. Staff, Instrument Software Engineer who is ready to bring their expertise to a high-impact environment and help us build a brand-new category of technology.

About the Role:

As a Senior Staff Instrument Software Engineer, you will be an essential member of our engineering team. You'll help architect, design, and implement high-performance software to operate the electrochemical CMOS based DNA synthesis instrumentation we are developing. You will also help support the development of a new generation of electronic gene sequencing hardware. All the hardware tightly integrates with back-end web services and bioinformatics pipeline.

• BS in Computer Science or related technical field
• Proficiency in C# and/or C++
• 6+ years industry experience
• Mastery of object oriented programming concepts, and clean software architecture design
• Familiarity with hardware integration, system bring-up and validation
• Ability to take a hands-on approach to software and hardware development
• Experience with Git or similar version control systems

Your responsibilities will include:

• Developing high-performance systems capable of handling very large data payloads while ensuring end-to-end data integrity.
• Help developing software running our highly custom DNA data storage platform
• Working closely with hardware, electrical and chemistry teams to help define requirements and specifications.
• Architecting and implementing using languages such as C, C++ or Rust.
• Bringing expertise in Real-Time Operating Systems (RTOS) to inform architectural decisions that meet strict timing and reliability requirements for hardware control.

Required Skills:

• 10+ years of professional software development experience, with significant experience in a Staff-level or equivalent senior technical leadership role.
• Expertise in broad set of languages such as C, C++, rust, typescript or python.
• Deep, demonstrable understanding of memory management and allocation strategies across multiple languages and runtimes.
• Proven ability to write performant, low-latency, and highly optimized code, particularly when dealing with very large data payloads (multi-gigabyte to terabyte scale).
• Experience designing and implementing firmware and working with high-speed buses (SPI, 1G/10G Ethernet, USB…).
• Knowledge of Real-Time Operating Systems (RTOS) and their implications on system architecture and design.

Desired Skills:

• Prior experience working directly with hardware development, bring-up, and troubleshooting.
• Front-end development (typescript, React or similar frameworks)
• Understanding of FPGA and ASIC integration
• Familiarity with data storage technologies
• Experience with cloud platforms (AWS, Azure, GCP) for data storage and deployment infrastructure.
• Bachelor's or master’s degree in computer science, Electrical Engineering, or a related field.
• Mastery of object oriented programming concepts, and clean software architecture design
• Familiarity with hardware integration, system bring-up and validation
• Ability to take a hands-on approach to software and hardware development
• Image processing experience
• Experience with Git or similar version control systems

Preferred qualifications:

• Master's or PhD in Computer Science or related technical field
• Electrical and mechanical engineering experience is a big plus
• Experience with the latest .NET is a plus
• WPF experience is a big plus, and an eye for clean UI design is greatly appreciated
• Interest and ability to learn other programming languages as needed