Radiochemist

US101 Guidehouse Inc.

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US - MD, Bethesda Until 10/5/2026 3+ years exp H-1B sponsor history First posted August 6, 2026 Last posted August 6, 2026
Job description

Job Family:

Scientist


Travel Required:

None


Clearance Required:

Ability to Obtain Public Trust

What You Will Do:

We are currently searching for an experienced radiochemist to support the development of specialized molecular imaging probes in support of the NIH. This full time position is located in Bethesda, MD.

  • Manage the routine production of PET radiotracers, including maintaining thorough and accurate production documentation.

  • Synthesize, purify, and characterize novel PET imaging probes to support preclinical and clinical research programs.

  • Develop and optimize radiolabeling methods for new imaging probes.

  • Produce tracers to support preclinical and clinical research and transition promising radiotracers from research-scale synthesis to GMP-compliant production when appropriate.

  • Develop, optimize, validate, and troubleshoot radiolabeling methods for emerging molecular imaging agents and translational research applications.

  • Collaborate with multidisciplinary teams to design, produce, and deliver novel molecular imaging probes.

  • Adhere to GMP, radiation safety, laboratory safety, and institutional quality standards while working with radioactive materials and radiopharmaceutical production systems.

  • Analyze experimental data, prepare technical reports, and communicate findings through written documentation, presentations, and scientific discussions.

What You Will Need:

  • Master’s degree

  • Minimum of THREE (3) years of radiochemistry experience. 

  • Demonstrated expertise in the synthesis of novel positron emission tomography (PET) imaging probes, particularly those labeled with fluorine-18 (18F) and zirconium-89 (89Zr).

  • Experience with automated synthesis platforms including GE TRACERlab and Trasis AllinOne modules is highly desirable.

  • Experience with Good Manufacturing Practice (GMP) radiopharmaceutical production.

  • A strong background in radiochemistry and analytical chemistry.

  • Must be able to obtain and maintain a Federal or DoD Public Trust. Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse. Candidates with an active Public Trust or existing suitability are preferred.

What Would Be Nice To Have:

  • PhD preferred. 

  • Excellent problem-solving skills and the ability to work effectively in a collaborative, service-oriented research environment.

  • Strong written and verbal communication skills.

  • Able to work independently and in a team setting.

  • Outstanding interpersonal and time management skills.

  • Demonstrated experience in staff training and mentoring.

The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.


What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

  • Medical, Rx, Dental & Vision Insurance

  • Personal and Family Sick Time & Company Paid Holidays

  • Parental Leave

  • 401(k) Retirement Plan

  • Group Term Life and Travel Assistance

  • Voluntary Life and AD&D Insurance

  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

  • Transit and Parking Commuter Benefits

  • Short-Term & Long-Term Disability

  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

  • Employee Referral Program

  • Corporate Sponsored Events & Community Outreach

  • Care.com annual membership

  • Employee Assistance Program

  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com.  Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse.  Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

About this role

Summary

Develop, synthesize, and optimize PET radiotracers for preclinical and clinical research.

Job title

Radiochemist

Experience level

3+ years

Minimum experience

3+ years exp

Industry

healthcare

Location requirements

Bethesda, MD, on-site; remote not specified

Salary

$74k–$124k

Visa sponsorship

H-1B sponsor history

Management role

No

Skills & keywords

Required skills

radiochemistryPET imaging probesfluorine-18 (18F)zirconium-89 (89Zr)GMP radiopharmaceutical production

Preferred skills

PhDautomated synthesis platformsGE TRACERlabTrasis AllinOneproblem-solvingcommunicationstaff training

Specializations

radiochemistryPET imagingradiolabelingGMP production
Locations

Structured locations inferred from the posting.

Bethesda, MD, USA

On-site City