Principal Data Scientist - Manufacturing & Supply Chain

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Boston, MA Until 8/22/2026 First posted March 25, 2025 Last posted March 25, 2025
Job description

Job Description

Are you passionate about leveraging data to shape the future of healthcare? Do you have experience applying machine learning and advanced analytics to manufacturing and supply chain challenges? Are you looking for an opportunity to tackle compelling business problems in the life sciences while growing your skillset as part of a collaborative team? You might be the perfect fit for our team.  

Our enterprise-wide data science, data engineering and product team seeks a data scientist with expertise in manufacturing data analytics, statistics, and machine learning, combined with a passion for solving business challenges through data-driven solutions. You will work on a highly collaborative, centralized team of data scientists, engineers, and strategists to deliver analytical insights and data products that drive value and impact for our highest priority business needs. You’ll work side-by-side with internal partners across development, clinical, commercial, manufacturing operations, and general and administrative areas to develop creative solutions that contribute meaningfully to our business and patients. 

Key Duties and Responsibilities:

  • Collaborate with a centralized team of data scientists/engineers/strategists and cross-functional partners to conceptualize, develop, and deploy data science solutions for highest priority business problems and to design and execute A/B tests to quantify the value of these solutions
  • Be the primary technical lead focused on creative use of diverse data sources to solve business problems, such as manufacturing batch record data, process characterization data, Quality Control data, Quality Assurance data, and supply chain data
  • Build and deliver compelling data visualizations and outputs to communicate findings to technical collaborators, non-technical audiences, and business leaders  
  • Participate in the broader data science community to stay current with methodology, software, and data development and availability  
  • Bring an entrepreneurial and ethical mindset, openness, transparency, and collegiality to your work

Knowledge & Skills:

  • Domain knowledge in biopharmaceutical manufacturing data, supply chain data, and/or related data sources
  • Expertise in programming languages (e.g. Python, R, SQL, JavaScript), version control, and other data science related tools (e.g. AWS, dbt)  
  • Extensive experience with statistical/analytical methodologies and machine learning algorithms (e.g. classification, regression, clustering, feature selection/engineering, deep learning, time-series analysis, network analysis, hypothesis testing)  
  • Comfortable working with both technical and non-technical staff in a fast-paced environment to come up with solutions/algorithms and create working prototypes
  • Exceptional communication skills and ability to present findings to non-technical audiences with effective data visualization approaches
  • Knowledge of the biopharma or healthcare industry preferred

Education & Experience:

  • PhD in Mathematics, Statistics, Biostatistics, Epidemiology, Computer Science, Clinical/Biomedical Informatics or a related computational and quantitative discipline and 3+ years of relevant experience, or a Master’s degree (computational/quantitative field of study) and 5+ years of relevant experience
  • Demonstrated ability to build and manage relationships with various cross-functional collaborators and stakeholders across the company
  • Experience with LLM prompt engineering and familiarity with creating LLM-based solutions and architectures such as retrieval-augmented generation preferred
  • Experience with developing advanced data visualizations and dashboards (e.g. Dash, Streamlit, R Shiny and front-end frameworks such as Flask and Angular) in business settings is a plus
  • Experience with Operations Research and manufacturing for biologics preferred

Pay Range:

$146,500 - $219,800

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 
 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

About this role

Summary

Leverage data science to solve manufacturing and supply chain challenges in healthcare.

Job title

Principal Data Scientist - Manufacturing & Supply Chain

Experience level

3+ years

Industry

biotechnology

Location requirements

Boston, MA; hybrid work option available

Salary

$146,500 - $219,800

Management role

No

Skills & keywords

Required skills

biopharmaceutical manufacturingsupply chainpythonrsqljavascriptawsdbtstatistical methodologiesmachine learningdata visualizationcommunication

Preferred skills

biopharmallm prompt engineeringdata visualizationsoperations research

Specializations

manufacturingsupply chainmachine learningdata analyticsstatistics
Locations

Structured locations inferred from the posting.

Boston, MA, USA

Hybrid City