Postdoctoral Research Fellow

Site: The Brigham and Women's Hospital, Inc.

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

Job Summary

Postdoctoral position available to study mechanisms of response to immune checkpoint inhibitors in kidney cancer.

Immunotherapy with immune checkpoint inhibitors (e.g. anti-PD-1/PD-L1 agents) has demonstrated clinical efficacy in metastatic renal cell carcinoma (mRCC). Unfortunately, only a subset of mRCC patients responds to these agents. To guide further clinical development of immune checkpoint inhibitors in kidney cancer, we aim to 1) develop and validate tissue-based predictors of drug response using both genomics approaches and in situ analyses; 2) understand the mechanism of action of PD-1/PD-L1 blockade to facilitate the development of highly active combination regimens.

 

The salary range for this position is $70,000 to $ 71,750 annually.

Requirements: We are seeking a highly motivated applicant with an M.D. or M.D./Ph.D. with formal training in Anatomic Pathology (at least 1 year in residency program) and laboratory experience in pathology and/or molecular biology. Background in bioinformatics/computational biology is desirable. Excellent written and oral communication skills are required. The candidate must be willing to commit to the position for at least two years.

If interested, please send a cover letter, CV and three references to:

Sabina Signoretti M.D.
Department of Pathology
Brigham and Women's Hospital
Thorn Building 504A
75 Francis Street
Boston, MA 02115
617-525-7437 (phone)
ssignoretti@bwh.harvard.edu

 

 

Onsite

 

75 Francis Street

 

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

 

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