Bench Scientist
Integrated Resources INC
Apply to this jobA Few Words About Us - Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.
• A position is available for a skilled bioanalytical scientist to join a state-of-the-art mass spectrometry laboratory in PDM with deep expertise in protein quantitation.
• The lab based role entails the development of sensitive quantitative assays for proteins targeted by therapeutics to provide information on target concentration ranges in serum or for proteins bio therapeutics to quantify the effect of anti-drug antibodies in the context of unwanted immunogenicity.
• This position requires bioanalytical expertise, expertise in immunoanalytical procedures, solid background in protein biochemistry, and triple quadrupole quantitative mass spectrometry.
• The candidate will participate in all phases of mass spec laboratory operations including the development of sample preparation and separation methods, assay execution, instrument maintenance, data analysis and reporting.
• We are looking for a scientist passionate about learning and quickly applying new skills to the project needs.
Responsibilities:
• Apply existing protein quantitation workflows using bead and column based immunoaffinity enrichment including the use of liquid handling robotics.
• Run bioanalytical assays under minimal supervision; initiative in method development is expected.
• Independent daily operation, calibration, maintenance, and troubleshooting of multi-dimensional nanoliquid chromatography and nanospray triple quadrupole mass spectrometry instrumentation.
• Support analysis of quantitative LC-MS/MS data using relevant bioinformatics and quantitation software.
• BS/MS level education in biochemistry, biology or chemistry or related fields required; advanced degree may be a plus.
• Industry experience in bio-pharma preferred.
• Expertise in the operation and maintenance of mass spectrometers.
• Experience with basic and complex quantitative protein LC-MS/MS assays.
• Track record of method development skills particularly with novel and complex methods applied to bioanalytical questions.
• Work well both independently and as part of a team.
• Collaborative skills and effective partnering skills in a matrix-environment.
• Strong data organization and analysis skills.
• Strong communication skills.
Position (ADA assay):
Phase 1: basic training (3m)
Phase 2: develop ADA LCMS assay concept (6m)
Phase 3: apply to clinical test sample set (3m)
Phase 4: refine and apply to further clinical sample sets (18m)
Phase 5: write publications on this subject (6m)
Thanks
Warm Regards
Ricky Bansal
732-429-1925
Summary
Develop and run bioanalytical assays using mass spectrometry for protein quantitation in a biotech lab.
Job title
Bench Scientist
Experience level
BS/MS level education
Industry
biotech
Location requirements
Andover, MA, US; remote not specified
Salary
Not specified
Visa sponsorship
H-1B sponsor history
Management role
No
Required skills
Preferred skills
Specializations
Structured locations inferred from the posting.
Andover, MA, USA