Senior Director, Portfolio & Program Management
Vertex US Distribution
Sourced from Vertex US Distribution's careers site · verified 7 hours ago
Job Description
General Summary:
The Senior Director, Portfolio & Program Management is a global role within the Program and Portfolio Management (PPM) organization. The incumbent is responsible for championing cross-functional project management excellence to programs across the drug development lifecycle (Research, Pre-clinical and Clinical Development, Registration and Commercialization). The incumbent is expected to lead the application of project management to identify opportunities, shape objectives and drive execution of global strategy for cross-functional drug development teams and portfolio operations initiatives. This role is a key leadership position within PPM, with accountability for the performance and end results of a department/area.
Key Duties and Responsibilities:
Knowledge and Skills:
Education and Experience:
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$242,200 - $363,200Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Skills
- project and portfolio management
- options analysis
- strategic planning
- business case generation
- finance
- resource management
- cross-functional team leadership
- influence
- written communication
- oral communication
- presentation skills
- pharmaceutical drug discovery and development
- organizational skills
- manage multiple priorities
- collaboration
- stakeholder engagement
- business management
- portfolio management
- program management
- drug development
- cross-functional leadership
- pharmaceuticals
Summary
Lead cross-functional drug development programs and portfolio operations, shaping strategy, managing execution, and mentoring project management professionals.
Job title
Senior Director, Portfolio & Program Management
Experience level
12 years of experience; 5 years of management experience
Minimum experience
5+ years
Industry
biotechnology
Location
Boston, MA · Hybrid
Salary
$242k–$363k
Listed in the job description
Management role
Yes
- Nov 5, 2026 First posted
- Nov 5, 2026 Live now
As observed on the employer's careers site by ApplyAll. We show every change we've seen including removals.
Posting history
- Nov 5, 2026 First posted
- Nov 5, 2026 Live now
As observed on the employer's careers site by ApplyAll. We show every change we've seen including removals.
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